A condition that involves very high levels of waste products in the blood.

Uremia happens when the kidneys no longer filter blood as they should, such as with chronic kidney disease or kidney failure. Uremia can be life-threatening without treatment.

Uremia symptoms can include extreme tiredness, upset stomach, loss of appetite, confusion and breath that may have a fishy odor.

Uremia treatments include a procedure called dialysis, which filters the blood when the kidneys no longer can. Or transplant surgery can replace a damaged kidney with a healthy donated one.