Glioma treatment usually begins with surgery. But surgery isn't always an option. For example, if the glioma grows into important parts of the brain, it might be too risky to remove all of the glioma. Other treatments, such as radiation therapy and chemotherapy, might be recommended as the first treatment.
Which treatments are best for you will depend on your particular situation. Your health care team considers the type of glioma, its size and where it's located in the brain. Your treatment plan also depends on your health and your preferences.
Treatments to control symptoms
If your glioma is causing symptoms, you might need medicine to make you more comfortable. Which medications you need depends on your situation. Options might include:
- Medicine to control seizures.
- Steroid medicines to reduce brain swelling.
- Medicine to improves alertness if you have severe fatigue.
- Medicine to help with thinking and memory problems.
Surgery
Glioma treatment usually starts with an operation to remove the glioma. Surgery might be the only treatment needed if all of the glioma is removed.
Sometimes the glioma can't be removed completely. The surgeon may remove as much of the glioma as is possible. This procedure is sometimes called a subtotal resection. It might be needed if the glioma can't easily be separated from the healthy brain tissue. It can also happen if the glioma is in a sensitive part of the brain. Even removing a portion of the tumor may help reduce your symptoms.
Surgery to remove a glioma carries risks. These include infection and bleeding. Other risks may depend on the part of your brain in which your tumor is located. For instance, surgery on a tumor near nerves that connect to your eyes may carry a risk of vision loss.
Radiation therapy
Radiation uses beams of powerful energy to kill tumor cells. The energy can come from X-rays, protons or other sources.
For glioma treatment, radiation therapy is often used after surgery. The radiation kills any glioma cells that might remain after surgery. Radiation is often combined with chemotherapy.
Radiation therapy might be the first glioma treatment if surgery isn't an option.
During radiation therapy, you lie on a table while a machine aims energy beams at specific points on your head. The beams are carefully programmed to deliver precise amounts of radiation to the glioma. A common schedule for radiation therapy is having treatments five days a week for a few weeks.
Side effects of radiation therapy depend on the type and dose of radiation you receive. Common side effects that happen during or soon after radiation include fatigue, scalp irritation and hair loss.
Chemotherapy
Chemotherapy uses drugs to kill tumor cells. Chemotherapy medicines are most often taken in pill form or injected into a vein. In certain situations, the chemotherapy can be applied directly to the glioma cells.
Chemotherapy is usually used in combination with radiation therapy to treat gliomas.
Side effects of chemotherapy depend on the type and dose of medicines you receive. Common side effects include nausea and vomiting, hair loss, fever and feeling very tired. Some side effects may be managed with medication.
Tumor treating fields therapy
Tumor treating fields therapy is a treatment that uses electrical energy to hurt the glioma cells. The treatment makes it hard for the cells to make new glioma cells.
Tumor treating fields therapy is used to treat an aggressive type of glioma called glioblastoma. This treatment is often done at the same time as chemotherapy.
During this treatment, sticky pads are attached to the scalp. You might need to shave your head so the pads can stick. Wires connect the pads to a portable device. The device generates an electrical field that hurts the glioma cells.
Side effects of tumor treating fields therapy include skin irritation where the pads are applied to the scalp.
Targeted therapy
Targeted therapy treatments focus on specific chemicals present within cancer cells. By blocking these chemicals, targeted therapy treatments can cause cancer cells to die.
Your glioma cells may be tested to see if targeted therapy might help you. For slow-growing gliomas, targeted therapy is sometimes used after surgery if the glioma can't be removed completely. For other gliomas, targeted therapy might be an option if other treatments haven't worked.
Side effects depend on the medicine used and the dose given.
Rehabilitation after treatment
Glioma and glioma treatment can hurt parts of the brain that help you move your body and control your thinking. After treatment you might need help to regain your ability to move, speak, see and think clearly. Treatments that might help include:
- Physical therapy, which can help you regain lost motor skills or muscle strength.
- Occupational therapy, which can help you get back to your daily activities, including work, after a brain tumor or other illness.
- Speech therapy, which can help if you have difficulty speaking.
- Tutoring for school-age children, which can help kids cope with changes in memory and thinking after a brain tumor.