Gastroenterology and Hepatology

Ongoing Projects

Sponsor Protocol Code Trial Name Principal Investigator Phase Therapeutic Area Diseases and Conditions
GSK 222291 A Dose-Finding, Double-Blind, Placebo-Controlled Phase 2b Study to Evaluate the Efficacy and Safety of GSK4532990 in Adults with Alcohol-related Liver Disease (ALD) -STARLIGHT SÜLEYMAN CİHAN YURDAYDIN (Prof.Dr.) Phase 2b Gastroenterology and Hepatology Liver Disease
89BIO Inc. BIO89-100-132 A Phase 3 Study to Evaluate the Efficacy and Safety of Pegozafermin in Subjects with Compensated Cirrhosis due to Metabolic Dysfunction-Associated Steatohepatitis (MASH) MÜJDAT ZEYBEL (Prof.Dr.) Phase 3 Gastroenterology and Hepatology Liver Disease
Boehringer Ingelheim 1404-0044 A randomised, double-blind, placebo-controlled, multicentre,
Phase III trial evaluating long-term efficacy and safety of
survodutide weekly injections in adult participants with non cirrhotic non-alcoholic steatohepatitis/metabolic associated steatohepatitis (NASH/MASH) and (F2) - (F3) stage of liver
fibrosis
MÜJDAT ZEYBEL (Prof.Dr.) Phase 3 Gastroenterology and Hepatology Liver Disease
Boehringer Ingelheim 1404-0064 A Phase III double-blind, randomised, placebo-controlled trial to
evaluate liver-related clinical outcomes and safety of once weekly
injected survodutide in participants with compensated non alcoholic steatohepatitis/metabolic dysfunction associated
steatohepatitis (NASH/MASH) cirrhosis
MÜJDAT ZEYBEL (Prof.Dr.) Phase 3 Gastroenterology and Hepatology Liver Disease
89BIO Inc. BIO89-100-131 A Phase 3 Study to Evaluate the Efficacy and Safety of
Pegozafermin in Subjects with Metabolic Dysfunction-Associated
Steatohepatitis (MASH) and Fibrosis
MÜJDAT ZEYBEL (Prof.Dr.) Phase 3 Gastroenterology and Hepatology Liver Disease
Bluejay Therapeutics, Inc. BJT-778-301 A Global, Randomized, Open-label, Multicenter, Phase 2b/3 Trial Evaluating BJT-778 vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (AZURE-1) SÜLEYMAN CİHAN YURDAYDIN (Prof.Dr.) Phase 2b/3 Gastroenterology and Hepatology Chronic Hepatitis D (HDV) Infection
Johnson and Johnson 77242113CRD3001 A Phase 2b/3 Randomized, Double-blind, Placebo-Controlled, Parallel Group, Multicenter Protocol to Evaluate the Efficacy and Safety of Icotrikina in Participants with Moderately to Severely Active Crohn’s Disease ALPER YURCİ (Prof.Dr.) Phase 2 Gastroenterology and Hepatology Inflammatory Bowel Disease
Gilead Sciences, Inc. GS-US-567-6968 Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta SÜLEYMAN CİHAN YURDAYDIN (Prof.Dr.) Phase 2 Gastroenterology and Hepatology Chronic Hepatitis D (HDV) Infection